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彭福佐 Fu-Chuo Peng

副教授 

電話:(02)23123456 #88609

傳真號碼(02)23410217

電子信箱:fcpeng@ntu.edu.tw


個人檔案

1964 - 1967
Junior Technician, Institute of Biochemistry, College of Medicine, National Taiwan University

1982 - 1987
Junior Technician, Bureau of Environmental Protection, Department of Public Health Executive Yuan
1987 - 1988
Senior Technician, Bureau of Environmental Protection, Department of Public Health Executive Yuan
1988 - 1992
Senior Technician, Environmental Protection Agent, Executive Yuan
1992 - 2006
Instructor, Institute of Toxicology, College of Medicine, National Taiwan University
2006 - present
Associate Professor, Institute of Toxicology, College of Medicine, National Taiwan University

究成果

(A).REFEREED PAPER(1998-now)

  1. JW Chen, YL Luo, MJ Hwang, FC Peng, and KH Ling (1999) Territrem B, a tremorgenic mycotoxin that inhibits acetylcholinesterase with noncolalent yet irreversible binding mechanism. Journal of Biological Chemistry. 274, 34916-34923. (SCI)
  2. FC Peng, SW Lin Wu, and BL Wag (2001) Metabolism of territrem A by liver microsomes of Wistar rats: identification of the metabolites and their metabolic pathway. Journal of Toxicology and Environmental Health Part A. 64, 579-593. (SCI)
  3. FC Peng, SW Lin Wu, and JL Lin (2001) Metabolism of territrem A by liver microsomes of Wistar rats: Sex differences and regulation with gonadal hormones and phenobarbital. Journal of Toxicology and Environmental Health Part A. 64, 661-671. (SCI)
  4. SY Fang, QK Wei, and FC Peng* (2002) Determination of territrem B in rice meida with different strains of Aspergillus terreus by chromatography. Journal of Food and Drug Analysis. 10, 159-163. (SCI)
  5. FC Peng, and SW Lin Wu (2002) Metabolism of territrem A by liver microsomes of Wistar rats: Cytochrome P450 isoforms catalyzing TRA metabolism. Journal of Toxicology and Environmental Health Part A. 65, 2163-2175. (SCI)
  6. SY Fang, and FC Peng* (2003) Factors affecting on territrem B production by Aspergillus terreus CCRC 32111 in Potato-Dextrose medium. Journal of Food and Drug Analysis. 11, 27-31. (SCI)
  7. SW Lin Wu, WC Jean, RJ Edwards, FC Peng* (2003) Cytochrome P4503A1 catalyzes the formation of MA1 from territrem A in liver microsomes of 7-week-old female Wistar rats. Journal of Toxicology and Environmental Health Part A. 66:453-467. (SCI)
  8. FC Peng, HY Tseng, JC Tasi, C Lin, and J Döehmer (2003) Role of human hepatic cytochrome P450s in territrem A metabolism. Journal of Toxicology and Environmental Health Part A. 66:1237-11248. (SCI)
  9. FC Peng, HH Chaing, SH Tang, PC Chen, and SC Lu. (2004, Jan) NADPH-cytochrome P450 reductase is involved in flunitrazepam reductive metabolism in Hep G2 and Hep 3B cells. Journal of Toxicology and Environmental Health Part A. 67:109-124. (SCI)
  10. FC Peng, CH Cheng, JC Liu, MF Wu, SH Lee, HJ Pan. (2004, Jun) Production of polyclonal antibodies against territrem B and detecion of territrem B in the conidia of Aspergullus terreus 23-1 by immunoelectron microscopy. Journal of Agricutural and Food Chemistry 52:3360-3365. (SCI)
  11. FC Peng, PC Chen, YJ Teng, RJ Edwards. (2005, Feb) Metabolism of territrem B and C in liver microsomes from 14-wk-old Wistar rats is catalyzed by cytochrome P-450 3A. Journal of Toxicology and Environmental Health Part A. 68:299-314. (SCI)
  12. FC Peng, SH Tang, MC Huang, CC Chen, TL Kuo, SJ Yin. (2005, Sep) Oxidative status in the patients with alcohol dependence: A clinical study in Taiwan. Journal of Toxicology and Environmental Health Part A. 68:1497-1509. (SCI)
  13. FC Peng, WC Jian, RJ Edwards. (2005, Nov) Profile of territrem metabolism and cytochrome P-450 3A expression in liver microsomes from Wistar rats of both genders as a function of age. Journal of Toxicology and Environmental Health Part A. 68:1871-1888. (SCI)
  14. FC Peng, CC Chang, CY Yang, RJ Edwards, J Doehmer (2006) Territrm B and C metabolism in human liver microsomes: Major role of CYP3A4 and CYP3A5. Toxicology 218:172-185.
  15. Chen CL, Chang PL, Lee SS, Peng FC, Kuo CH, Chang HT. (2007) Analysis of magnolol and honokiol in biological fluids by capillary zone electrophoresis. J Chromatogr A. 1142(2):240-244.
  16. FC Peng*, YL Chen, PF Searle (2007) Nitroreductase Catalyzing Flunitrazepam Reductive Metabolism. Toxicology (submitted). (SCI) (NSC-95-2320-B-002-100)
  17. CL Peng, PL Chang, LL Lee, FC Peng, CH Kuo, HT Chang (2007) Analysis of magnolol and honokiol in biological by capillary zone electrophoresis. Journal of Chromatography A 1142:240-244. (NSC-95-2320-B-002-113, NSC 95-2113-M-002-026-MY3)
  18. YH Lin, FC Peng* (2008) Predicting the contribution of rat cytochrome P450 3A1, 3A2 and human cytochrome P450 3A4, 3A5 to territrem A 4b-C hydroxylation using the relative activity factor. Journal of Toxicology and Environmental Health Part A. (Accepted) (NSC-95-2320-B-002-100)
  19. MC Huang, CC Chen, FC Peng*, SH Tang, CH Chen. The correlation between early alcohol withdrawal severity and oxidative stress in patients with alcohol dependence. Progress in Neuro-psychoparmacology and Biological Psychiatry. 2009, 33: 66- 69.
  20. SW LinWu, CJ Syu, YL Chen, Andrew HJ Wang*, FC Peng*. Characterization of Escherichia coli nitroreductase NfsB in the metabolism of nitrobenzodiazepines. Biochemical pharmacology , 2009, 78:96-103.
  21. MC Huang, CH Chen, FC Peng, SH Tang, CC Chen. Alterations in oxidative stress status during early alcohol withdrawal in alcohol patients. Journal of Formosal Medicine Association, 2009, 108:560-569.
  22. Li, Pei-Ru, Wei, Jiun-Chiouk, Chiu, Ying-Fang, Su, Hong-Lin, Peng, Fu-Chuo, Lin, Jiang-Jen. Evaluation on Cytotoxicity and Genotoxicity of the Exfoliated Silicate Nanoclay. ACS Appl. Mater. Interfaces, 2010, 2 (6), pp 1608–1613.
  23. LinWu SW, Wang AH, Peng FC. Flavin-containing reductase: new perspective on the detoxification of nitrobenzodiazepine. Expert Opin Drug Metab Toxicol. 2010 Aug;6(8):967-81.
  24. Kuo CH, Lee CW, Lin SC, Tsai IL, Lee SS, Tseng YJ, Kang JJ, Peng FC, Wei-Chu L. Rapid determination of aristolochic acids I and II in herbal products and biological samples by ultra-high-pressure liquid chromatography-tandem mass spectrometry. Talanta. 2010 Mar 15;80 (5):1672-80.
  25. Wu MF, Peng FC, Chen YL, Lee CS, Yang YY, Yeh MY, Liu CM, Chang JB, Wu RS, Yu CC, Lu HF. Evaluation of genotoxicity of Antrodia cinnamomea in the Ames test and the in vitro chromosomal aberration test. In Vivo. May-Jun 25(3):419-423.
  26. LinWU SW, Wu CA, Peng FC, Wang AH. Structure-based development of bacterial nitroreductase against nitrobenzodiazepine-induced hypnosis. Biochem Pharmacol. 2012, Jun 15; 83(12):1690-1699.
  27. Chu CY, Peng FC, Chiu YF, Lee HC, Chen CW, Wei JC, Lin JJ. Nanohybrids of silver particles immobilized on silicate platelet for infected wound healing. PLoS One, 2012, 7:e3860.​

​(B).CONFERENCE PAPER

  1. FC Peng, BL Wang, and JL Lin (1998) Metabolism of territrem A by liver microsomes from Wistarrats and its regulation by sex hormone. Symposium in the Thirteenth Jiont Conference of Biomedical Science. Taipei, TAIWAN. p.220.
  2. JW Chen, YL Luo, MJ Hwang, FC Peng, and KH Ling (2000) Territrem B, a tremorgenic mycotoxin that inhibits acetylcholinesterase yet irreversible binding mechanism. Symposium in the Fifteenth Jiont Conference of Biomedical Science. Taipei, TAIWAN. p. 141
  3. SW Lin Wu, and FC Peng* (2000) Role of cytochrome P450 involment in TRA metabolism. Symposium in the Fifteenth Jiont Conference of Biomedical Science. Taipei, TAIWAN. p. 151.
  4. FC Peng, HH Chaing,and SH Tang (2003) NADPH-cytochrome P450 reductase is involved in flunitrazepam reductive metabolism. Symposium in the eighteenth Jiont Conference of Biomedical Science.
  5. WC Jian, and FC Peng, (2004) Gender- and age-related changes in territrem metabolism by liver microsomes from Wistar rats. Japanese Association for Laboratory Animal Science (JALAS) International Award.Kagasaki, Japan. P.58.
  6. FC Peng, SH tang, MC Huang, CC Chen, TL Kuo, SJ Yin. (2004) Oxidative status in the patients with alcohol dependence: A clinical study in Taiwan. Symposium in Oxidative Damage Marker and Antioxidant Intervention in Health and Diseases. Taiwan. p.47.
  7. SH Tang, CC Chen, FC Peng (2005) Alcohol dependence and oxidative status. Symposium in the Twentieth Jiont Conference of Biomedical Science. Taipei, TAIWAN. p. 280.
  8. PC Chen, FC Peng (2005) Metabolism of territrem B and C in liver microsomes from 14-wk-old Wistar rats is catalyzed by cytochrome P4503A. Symposium in the Twentieth Jiont Conference of Biomedical Science. Taipei, TAIWAN. p. 671.
  9. FC Peng (2005) The location of territrems in the fungal body of Aspergillus terreus and cytochtrome P450 3A involving transformation of territrems. 3rd Strait Bilteral Symposium on toxicology p. 4.
  10. YL Chen, FC Peng (2005) Reductive metabolism of flunitrazepam with reference to nitroreductase. 中華實驗動物學會:第八屆二次會員大會暨學術研討會P34.
  11. FC Peng, CC Chang (2006) Territrem B and C metabolism in human liver microsomes: Major role of CYP3A4 and CYP3A5. The 21th Joint Annual Conference of Biomedical Science. Taipei, Taiwan.p.95.
  12. YL Chen, FC Peng (2007) 7-aminoflunitrazepam formation metabolized by nitroreductase. The 22th Joint Annual Conference of Biomedical Science. Taipei, Taiwan. p. 110.
  13. CW Huang, CH Huang, TY Ling, FC Peng (2008) The study for signal pathway of paraquat induced cell death in mice pulmonary clara cell-related stem/progenitor cells. The 23th Joint Annual Conference of Biomedical Science. Taipei, Taiwan. p.30.​


*Author for correspondence
#撰稿人之一

(C).Other Publication
於幼華,彭福佐#等(2002)環境科學大辭典,文景書局印行.