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​​biing.jpg劉秉慧 Biing-Hui Liu

教授 

電話:886-2-2312-3456 #88602
傳真:886-2341-0217
電子信箱:biingliu@ntu.edu.tw

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​​個人檔案​

主要學歷

威斯康辛大學-Madison,分子及環境毒理學博士 
台大理學院生化科學碩士 
台大農化系農製組學士

​主要經歷

2012.08~  迄今       臺大醫學院毒理學研究所教授
2006.06 ~ 2012.07  中山醫學大學生物醫學科學系教授
                                慈濟大學毒理所助理教授,
 

研究成果

  1. Wu, T. S., Yang, J. J., Wang, Y, W., Yu, F. Y*., Liu, B. H*. 2016. Mycotoxin ochratoxin A disrupts renal development via miR-731/prolactin receptor axis in zebrafish. Toxicology Research.  DOI: 10.1039/C5TX00360A
  2. Liu, B. H., Chu, K. C., Yu, F. Y. 2016. Novel monoclonal antibody-based sensitive enzyme-linked immunosorbent assay and rapid immune chromatographic strip for detecting aflatoxin M1 in milk. Food Control. DOI: 10.1016/j.foodcont.2016.01.036
  3. Liu, J. W., Lu, C. C., Liu, B. H*., Yu, F. Y*. 2015. Development of novel monoclonal antibodies-based ultrasensitive enzyme- linked immunosorbent assays and rapid immunochromatographic strips for aflatoxin B1 detection. Food Control. 59: 700 -707
  4. Liu, B. H., Hung, T, C., Lu, C. C, Chou, H. N., Yu, F. Y*. 2014. Production of monoclonal antibody for okadaic acid and its utilization in an ultrasensitive enzyme-linked immunosorbent assay and one-step immunochromatographic strip.
     Journal of Agricultural and Food Chemistry. 62:1254-1260.​​
  5. Liu, B. H., Hsu, Y. T, Lu, C. C, Yu, F. Y*.  2013. Detecting aflatoxin B1 in foods and feeds by using sensitive rapid enzyme-linked immunosorbent assay and gold nanoparticle immunochromatographic strip.  Food Control  30:184-189
  6. Wu, T. S. Yang, J. J. Yu, F. Y., Liu, B. H.*, 2013, Cardiotoxicity of mycotoxin citrinin and involvement of microRNA 138 in zebrafish embryos. Toxicological Sciences 2013. 136: 402-412.​
  7. Wu, T. S., Yang, J. J., Yu, F. Y., Liu, B. H*. 2012.Evaluation of nephrotoxic effects of mycotoxins, citrinin and patulin, on zebrafish embryos. Food Chem Toxicol. 2012 Dec;50(12):4398-404.
  8. Chang, C. H., Yu, F. Y., Wu, T. S., Wang, L. T., Liu, B. H*. 2011.Mycotoxin Citrinin induced cell cycle G2/M arrest and numerical chromosomal aberration a​ssociated with disruption of microtubule formation in human cells. Toxicological Sciences 119, 84-92.
  9. Liu, M. C, Lin, T. H., Wu, T. S., Lu, C. C., Liu, B. H.* 2011. Aristolochic acid I suppressed iNOS gene expression and NF-kB activation in stimulated macrophage cells. Toxicology Letter 202, 93-99.
  10. Yu, F. Y., Wu, T. S., Chen, T. W., Liu, B. H*. 2011. Aristolochic acid I induced oxidative DNA damage associated with glutathione depletion and ERK1/2 activation in human cells. Toxicology in vitro 25, 810-816.
  11. Liu, B. H, Chi J.-Y., Hsiao Y.-W.,Tsai, K.-D.., Lee Y.-J.., Lin C.-C, Hsu S.-C., Yang S.-M., Lin, T. H*. 2010. The fungal metabolite, citrinin, inhibits LPS/IFN-induced nitric oxide production in glomerular mesangial cells. International Immunopharmacology 10, 1608-1615.
  12. Chang,C. H. , Yu, F. Y., Lin, Y. S.,, Wang, L. T., Liu, B. H*. 2009. Activation of ERK and JNK signaling pathways by mycotoxin citrinin in human cells. Toxicology and Applied Pharmacology 237, 281-287.
  13. Wu, T. S., Liao, Y. C., Chang, C. H., Liu, B. H.* 2008. Mechanism of patulin-induced apoptosis in human leukemia cell. Toxicology letter 183, 105-111.
  14. Liu, B. H., Tsao, Z. J., Wang, J. J., Yu, F. Y. 2008. Development of a monoclonal antibody against OTA and its application in gold nanoparticle immunochroimatograpyic strip. Analytical Chemistry 80, 7029-7035.
  15. Liu, B. H.*, Wu, T. S., Yu, F. Y., Su, C. C. 2007. Induction of oxidative stress response by the mycotoxin patulin in mammalian cells. Toxicological Sciences 95, 340-347.
  16. Liu, B. H*. Wu, T. S., Wang, C. H. 2006. Mycotoxin patulin activates p38 and JNK signaling pathways in human embryonic kidney cells. Toxicological Sciences 89, 423-430.
  17. Yu, F. Y., Liao, Y. C., Chang, C. H., Liu, B. H*. 2006. Citrinin induces apoptosis in HL-60 cells via activation of the mitochondrial pathway. Toxicology Letter 161, 143-151. ​